Developing S-phase control
نویسندگان
چکیده
منابع مشابه
11 Control of S Phase
Sustained cell proliferation requires the duplication and segregation between daughter cells of every cell constituent. Because chromosomes are present in only one or two copies per cell, their duplication and segregation are particularly tightly regulated. To ensure that daughter cells inherit at least one copy of each of their genes and to maintain an appropriate balance in their relative num...
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BACKGROUND Fast, early embryonic cell cycles have correspondingly fast S phases. In early Drosophila embryos, forks starting from closely spaced origins replicate the whole genome in 3.4 min, ten times faster than in embryonic cycle 14 and a hundred times faster than in a wing disc. It is not known how S phase duration is regulated. Here we examined prolongation of embryonic S phases, its coupl...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2012
ISSN: 0890-9369
DOI: 10.1101/gad.191171.112